We employ light to study and manipulate biological systems. Two key questions are currently in the focus of our research. The first one deals with a longstanding mystery in cell biology: How does the glycocalyx regulate, and how is it regulated by, cellular state? The second one is about novel therapeutic compounds: How can we use precise light activation of tailored substances to kill cancer cells at defined locations in the body without harming healthy tissue?

In our research, we combine state-of-the-art methods from diverse fields. We leverage multiple orthogonal techniques such as super-resolution microscopy, iSCAT microscopy, high-throughput imaging, and RT-DC.

Our research spans the spectrum from fundamental biophysics to clinical sciences. We are not satisfied with answering questions that we can address with the tools at hand. Rather, we identify urgent questions and establish the tools we need to answer them. With this integrated approach, we strive to unravel the role of the glycocalyx in health and disease and to unlock novel approaches for therapeutic intervention.

Find more information on our website.